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- Health Food,Pure Natural Drugs: Anticancer, Radioresistance, Antiviral
Source:.Mangiferin from mango tree leaves.
Proportion and content: 10: 1, 20: 1; 80%,90%,95%(HPLC)
GMP, Pure natural healthy food and pure natural plant medicine specifications: 500 mg * 100 particles /Bottle; 500 * 200 mg particles/Bottle, 100 bottles/Box; MOQ:100 boxes .
More information is as follows:
Active ingredients: Mangiferin
Mangiferin is light yellow powder.
Molecular formula and molecular weight:19 H C 18 O 11;422.33
CAS No. : 4773-96-0
Main ingredients mangiferin;Sources: mango leaves;Appearance: Powder;
Test method: HPLC;Content: the 95 (%);Application form: Powder
Clinical application: health care products and pharmaceutical excipients;Packing: aluminum foil bag;Shelf life: 36 (month)
Color: Yellow;Bouquet: special smell
100%Natural Mangiferin Main efficacy:
1. Remove disease cough, mangiferin on cough phlegm asthma disease have auxiliary therapy effect;
2. Heat effect;
3. The strong heart, diuresis, antidepressant, anti-inflammatory, antiviral effect;
4. The mangiferin has obvious anti lipid peroxide and protect brain neurons;
5. Mangiferin has obviously increase red blood cell hydrogen peroxide enzyme activity and reduce the effect of red blood cell hemoglobin.
The sterilization.Mango leaves extract can inhibit rotting aureus, escherichia coli, pseudomonas aeruginosa.At the same time also have the function of the inhibition of influenza virus.
Pharmacological function: This product has the inhibition of the central nervous system, anti-inflammatory, antibacterial, herpes simplex virus resistant HSV -2, cholagogic and immune function, alleviate the sacral nerve roots of HSV - 2 viruses cause disease, characterized by or strands of hip pain or abnormal sensation, urinary retention, it associated with disease and proctitis, urethritis syndrome, etc.The dangers of HSV - 2 viruses women cervical cancer 5 ~ 10 times greater than the average woman.Acute hypoxia of simulated plateau protects liver damage.Pharmacological experiments showed that this product is used in the treatment of chronic bronchitis has good curative effect, is the main effective components of herba artemisiae treatment hepatitis, is in the common anemarrhena rhizome antiviral active ingredient.
1. 100% of the natural and the effect of mangiferin on the central nervous:
Mangiferin has obvious central nervous system stimulant *, 50-100 mg/kg dose of intraperitoneal injection of mangiferin (jp) can make all the animals appear tremor, vertical hair, compulsive symptom such as tear and independent activity increases.The climax of the behavior change is 30 min after dosing and maintain to 60 min, gradually decline after 120 min.If experimental animals give chlorpromazine in advance 5 mg/kg, jp can block the mangiferin these effects, mangiferin might be mesolimbic system of D2 receptor agonist
In experimental animals 30 mg/kg, jp 30 min if given mangiferin before 50 mg/kg, jp can obviously prolong the sleeping time, first give the mangiferin rats sleep time for (56.2 56.2) min and blank control group (36.2 to 5.3) min doses of mangiferin can obviously strengthen the mild doses of ether anesthesia. 60% of the mice in the dose range loses its normal nerve reflex, and the blank control group, no this phenomenon.
2. 100% natural mangiferin respiratory function:
Mangiferin on guinea pig histamine and acetylcholine mixture lead asthma significantly prolong asthma incubation period;Concentrated ammonia in mice lead to cough can obviously prolong cough incubation period, and obviously reduce the mice cough;With the increase of celiac capillary permeability caused by acetic acid in mice
Obvious inhibition;Tracheal phenol red shedding in mice.
3. 100% natural mangiferin cardiovascular function:
1-2 mg dose of mangiferin in normal or low function in vitro Ringcrs fluid infusion frog heart are short, exact enhance the effect of myocardial contraction force, and the effect is not blocked , therefore, it can be a direct
4.100% natural mangiferin cardiac stimulants function:
Antiviral: mangiferin has I resistance in vitro model of herpes simplex virus (HSV - I), plaque decrement was 56.8%, the antiviral effect due to its ability to suppress viral replication in the cell.
5. 100% natural mangiferin role of radiation:
Mangiferin is a kind of natural antioxidants scavenging free radicals, is also a kind of natural radiation protective agent, its molecular structure of the four phenolic hydroxyl have electrophilic ability, is good energy trap and benzene ring, so can make the biological molecules must transfer the irradiation caused by free radicals, thus protecting biological molecules.
6.100% natural mangiferin antitumor effect:
In normal and tumor in mice in vivo or in vitro treatment, mangiferin could improve the spleen cells and peritoneal macrophage cytotoxic effect.
Mangiferin can effectively reduce doxorubicin (Dox) on the inhibition of the mitochondrial cytochrome C oxidase, and has no effect on the antitumor activity of Dox.
7. 100% natural - mangiferin the role of diabetes:
After oral mangiferin and glucoside, there were no changes in normal blood glucose level in mice, but can reduce the spontaneous diabetes animal model KK - Ay mice blood glucose concentration, and the trend of serum insulin levels also have lower.
Intraperitoneal injection of mangiferin, can obviously reduce diabetic rats caused by oxidative damage of glycosylation of hemoglobin and serum creatine phosphokinase (CPK).
8. 100% natural mangiferin protect liver cholagogic effect:
In rat liver lysosomal temperature hatch in vitro experiments have found that the role of mangiferin in stable lysosome membrane, and the lysosome acid phosphatase activity has a direct inhibitory effect
The effect of mangiferin
9. 100% natural other:
Mangiferin has antibacterial;Anti-inflammatory;Antifebrile and immune regulating effect.The pharmacological effects of mangiferin clear;Plant sources, at present is mainly used in clinical respiratory system disease. Although the mangiferin dissolved because the reason such as the poor performance in the clinical application of cuhk restricted, but its anti-cancer;Antiviral activity and resistance to diabetes, has been more and more get the attention of people. Believe that with the deepening of the research, mangiferin will have good development prospect.